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GO:0005852: eukaryotic translation initiation factor 3 complex (Cellular component)

"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]


There are 1229 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_355 Brassica rapa 50.0 % 0.000538 0.005109
Cluster_94 Brassica rapa 1.56 % 0.000525 0.002644
Cluster_47 Lactuca sativa 1.41 % 0.001169 0.004638
Cluster_179 Lactuca sativa 1.45 % 0.024546 0.049093
Cluster_130 Spinacia oleracea 6.0 % 0.0 7e-06
Cluster_95 Spinacia oleracea 1.56 % 0.012776 0.037889
Cluster_84 Marchantia polymorpha 1.8 % 0.00032 0.010924
Sequences (1229) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms