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GO:0004222: metalloendopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE]


There are 2044 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_269 Brassica rapa 4.11 % 0.000141 0.010521
Cluster_211 Brassica rapa 1.24 % 0.0045 0.040997
Cluster_171 Lactuca sativa 2.17 % 0.012032 0.045049
Cluster_9 Lactuca sativa 3.16 % 0.000686 0.003091
Cluster_87 Spinacia oleracea 1.45 % 0.001077 0.017738
Cluster_851 Spinacia oleracea 33.33 % 0.002922 0.016801
Cluster_44 Spinacia oleracea 1.57 % 0.006839 0.041562
Cluster_42 Spinacia oleracea 1.28 % 0.010154 0.031405
Cluster_3 Marchantia polymorpha 4.65 % 8e-06 0.001533
Sequences (2044) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms