Bra012132 (ICU2)

Aliases : ICU2

Description : catalytic component *(POLA1) of DNA polymerase alpha complex

Gene families : OG0012052 (OrthoFinder Output from 4 Species - Bra, Lsa, Mpo, and Sol) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Brassica rapa (Bra) PCC: Bra012132
Cluster	Brassica rapa (Bra) Coexpression Clusters (HCCA Algorithm): Cluster_189

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000808	origin recognition complex	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0003682	chromatin binding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0003896	DNA primase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0005524	ATP binding	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0005634	nucleus	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0005694	chromosome	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006270	DNA replication initiation	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006275	regulation of DNA replication	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006996	organelle organization	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0008168	methyltransferase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0010639	negative regulation of organelle organization	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0016043	cellular component organization	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0016070	RNA metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0017076	purine nucleotide binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0018130	heterocycle biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0030554	adenyl nucleotide binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0032392	DNA geometric change	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0032508	DNA duplex unwinding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0032553	ribonucleotide binding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0032555	purine ribonucleotide binding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0032774	RNA biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0032780	negative regulation of ATP-dependent activity	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0032991	protein-containing complex	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0033043	regulation of organelle organization	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0033044	regulation of chromosome organization	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0042555	MCM complex	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0042575	DNA polymerase complex	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0043086	negative regulation of catalytic activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0043167	ion binding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0043168	anion binding	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0043226	organelle	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0043227	membrane-bounded organelle	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0043229	intracellular organelle	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0043462	regulation of ATP-dependent activity	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0043625	delta DNA polymerase complex	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0044092	negative regulation of molecular function	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0044877	protein-containing complex binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0048478	obsolete replication fork protection	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0048519	negative regulation of biological process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0048523	negative regulation of cellular process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0050790	regulation of catalytic activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0051052	regulation of DNA metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0051095	regulation of helicase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0051097	negative regulation of helicase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0051128	regulation of cellular component organization	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0051129	negative regulation of cellular component organization	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0051276	chromosome organization	IEP	Brassica rapa GO terms from Neighborhoods
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0065009	regulation of molecular function	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0071103	DNA conformation change	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0071840	cellular component organization or biogenesis	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0097367	carbohydrate derivative binding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0097747	RNA polymerase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:1905774	regulation of DNA helicase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:2001251	negative regulation of chromosome organization	IEP	Brassica rapa GO terms from Neighborhoods

InterPro domains	Description	Start	Stop
IPR015088	Znf_DNA-dir_DNA_pol_B_alpha	1021	1223
IPR006133	DNA-dir_DNA_pol_B_exonuc	61	455
IPR006134	DNA-dir_DNA_pol_B_multi_dom	521	982

External Links

No external refs found!

Bra012132 (ICU2)

Expression Profile

Co-expression Networks

Functional Annotation