Bra002917 (TOP1BETA, TOP1)

Aliases : TOP1BETA, TOP1

Description : DNA topoisomerase *(TOP1)

Gene families : OG0011825 (OrthoFinder Output from 4 Species - Bra, Lsa, Mpo, and Sol) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Brassica rapa (Bra) PCC: Bra002917
Cluster	Brassica rapa (Bra) Coexpression Clusters (HCCA Algorithm): Cluster_262

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0003724	RNA helicase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0004175	endopeptidase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0004197	cysteine-type endopeptidase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0004386	helicase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0004743	pyruvate kinase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0004869	cysteine-type endopeptidase inhibitor activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006082	organic acid metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006401	RNA catabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006402	mRNA catabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0006508	proteolysis	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0008186	ATP-dependent activity, acting on RNA	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0008233	peptidase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0008234	cysteine-type peptidase activity	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0008289	lipid binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0009892	negative regulation of metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0010629	negative regulation of gene expression	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0019439	aromatic compound catabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0019752	carboxylic acid metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0030955	potassium ion binding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0031072	heat shock protein binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0031420	alkali metal ion binding	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0032182	ubiquitin-like protein binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0034655	nucleobase-containing compound catabolic process	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0043130	ubiquitin binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0043436	oxoacid metabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0044270	cellular nitrogen compound catabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0046700	heterocycle catabolic process	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0050790	regulation of catalytic activity	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:0065009	regulation of molecular function	IEP	Brassica rapa GO terms from Neighborhoods
MF	GO:0070403	NAD+ binding	IEP	Brassica rapa GO terms from Neighborhoods
BP	GO:1901361	organic cyclic compound catabolic process	IEP	Brassica rapa GO terms from Neighborhoods

InterPro domains	Description	Start	Stop
IPR008336	TopoI_DNA-bd_euk	363	574
IPR025834	TopoI_C_dom	838	906
IPR013500	TopoI_cat_euk	577	800

External Links

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Bra002917 (TOP1BETA, TOP1)

Expression Profile

Co-expression Networks

Functional Annotation