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GO:0003918: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2." [PMID:8811192]


There are 1295 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_370 Brassica rapa 50.0 % 0.00044 0.02156
Cluster_245 Lactuca sativa 50.0 % 0.000565 0.022613
Cluster_143 Spinacia oleracea 0.7 % 0.024185 0.048203
Sequences (1295) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms